Selected Publications

we have validated that patients with intermediate baseline serum tryptase levels (8-11 ng/mL) and without skin involvement have a higher risk of severe venom induced anaphylaxis.
JACI, 2021

We aimed to analyze the treatment courses of pemphigus patients and the clinical responses regarding therapy changes.
Front Med (Lausanne), 2020

We investigated adult patients with grass pollen–induced allergic rhinoconjunctivitis ± allergic asthma and low serum 25(OH)D.
Allergy, 2020

Atopic dermatitis (AD) is a frequent chronic remittent skin disease. The pathophysio-logy of AD has been increasingly better understood within the last years. This may help to identify different endotypes which are suitable for defined therapies. A patient oriented therapy considers besides phenotypical features also genetic and biologi-cal markers. The most recent developments regarding biologics and small molecule drugs are presented in this article. Such molecules will change the treatment perspec-tives for atopic dermatitis in the future if they will be approved. Dupilumab is the first approved biologic for the treatment of moderate to severe atopic dermatitis in adolescence and adulthood and has led to a significant impro-vement of the treatment of this chronic disease. In the present article we show real-li-fe data on the efficacy of dupilumab in adult dermatitis patients and discuss other relevant data, but also open questions, which are important for the standard care of atopic dermatitis patients.
JDDG, 2020

To uncover the mechanisms by which skin barrier disruption elicits TSLP production and to delineate the level at which individual mechanistic components may converge.
Br J Dermatol, 2020

In the present analysis, we aimed to evaluate the management and risk factors of refractory anaphylaxis to highlight possible clinical implications for updating current management algorithms.
Exp Rev Clin Immun, 2018

Preventive measures to decrease the frequency and intensity of anaphylactic events are essential to provide optimal care for allergic patients. Aggravating factors may trigger or increase the severity of anaphylaxis and therefore need to be recognized and avoided. Our data suggest it may be possible to identify patients who require intensified preventive measures due to their relatively higher risk for severe anaphylaxis by considering endogenous and exogenous factors.
Allergy, 2018

We read with great interest the article “Estrogen increases the severity of anaphylaxis in female mice through enhanced endothelial nitric oxide synthase expression and nitric oxide production” by Hox et al.1 Therein, the authors provide experimental evidence that female mice exhibit more severe anaphylactic reactions than do their male counterparts and offer mechanistic insights by showing that estrogen promotes vascular leakage during an anaphylactic event via enhanced nitric oxide production.
JACI, 2015

Recent Publications

More Publications

. Current developments in the treatment of peanut allergy. Aller J Inter, 2021.


. Use of biologics in food allergy management. Allergol Select, 2021.


. Phenotype and risk factors of venom-induced anaphylaxis: A case-control study of the European Anaphylaxis Registry. JACI, 2021.


. Therapy Changes During Pemphigus Management: A Retrospective Analysis. Front Med (Lausanne), 2020.

Source Document

. Immunomodulation of high‐dose vitamin D supplementation during allergen‐specific immunotherapy. Allergy, 2020.

Source Document

. Moderne Therapie der atopischen Dermatitis: Biologika und kleinmolekulare Medikamente. JDDG, 2020.

PDF Project

. Factors increasing the risk for a severe reaction in anaphylaxis: An analysis of Data from The European Anaphylaxis Registry. Allergy, 2018.

PDF Project

Recent & Upcoming Talks

Reproducibility in research
Mar 13, 2018 7:00 PM

Recent Posts

Today I was doing a quick ELISA and realized that the reader was old and produced the results in PDF only. This poses multiple problems as they need to be manually rewritten to a file and post-processed later. Additionally the optical density measurments in my software are automatically calculated into concentration based on some shady functions which I never understood. I decided to change this and learn this and that about analysing ELISA results.


Why do scientists still use journal articles as main form of sharing their research? The paper publication has been with the academics since ages and it surely does need an update. The variety of outputs we have to offer ar modern scientists had dramatically evolved and contains multigiabyte databases along with high quality images, and simple text output. We therefore need a modern medium which allows sharing such sophisticated data and paper simply is not suited for this.